Industry
The Most Popular Cannabis Strains in Lynn & Greater Boston (2025)
by Mike Feyler
March 8, 2025

The Massachusetts cannabis market continues to evolve, with new strain genetics, consumer trends, and cultivation advancements shaping what’s most in demand. Whether you're seeking a relaxing indica, an uplifting sativa, or a well-balanced hybrid, understanding what’s trending in 2025 can help you find the right strain for your needs.
This guide breaks down the most sought-after cannabis strains in Lynn, the North Shore, and Greater Boston, based on their popularity, effects, and market availability.
With On Root’s delivery service launching soon, getting your favorite strains will be even more convenient for North Shore consumers.
Top Cannabis Strains in Greater Boston & North Shore (2025)
Chem D (Hybrid) – The Massachusetts Classic
Originally bred by Massachusetts legend Chemdog, Chem D has solidified itself as a powerhouse strain with pungent diesel aromas, high potency, and a balanced hybrid effect. It delivers a strong cerebral rush followed by full-body relaxation, making it a go-to for both recreational and medicinal consumers.
Best for: Euphoria, creativity, and deep relaxation.
Super Boof (Hybrid) – The Flavor Powerhouse
This fruity, gassy hybrid has quickly climbed the ranks, gaining traction among Boston and North Shore cannabis consumers. With tropical, candy-like flavors and potent body relaxation, it’s an excellent choice for unwinding.
Best for: Evening relaxation, mood enhancement, and flavorful smoking sessions.
Gelonade (Sativa) – The Energizing Delight
A cross between Gelato #41 and Lemon Tree, Gelonade offers a bright citrus flavor and uplifting effects, making it ideal for daytime use. This strain is highly sought after for its energetic and creative boost—perfect for New England’s working professionals and artists.
Best for: Daytime motivation, creative projects, and social activities.
Grape Cream Cake #3 (Indica) – The Relaxation Specialist
This dessert-flavored indica hybrid is known for its rich, creamy grape taste and deeply soothing effects. Its ability to melt away stress and promote sleep has made it one of the most popular nighttime strains in Massachusetts dispensaries.
Best for: Evening use, stress relief, and deep relaxation.
Dawgwaltz (Indica) – The Sleep Inducer
Dawgwaltz has developed a cult following among indica lovers in Massachusetts. With sedative properties and a skunky, earthy flavor, it’s ideal for those seeking deep relaxation and insomnia relief.
Best for: Nighttime use, pain relief, and sleep support.
Strain Trends in Greater Boston: What’s Coming Next in 2025
Terpene-Heavy Strains Are Taking Over
Consumers are moving beyond just high-THC strains and prioritizing cannabis with strong, complex terpene profiles. Terpenes influence both flavor and effects, and in 2025, strains with distinctive aromatic qualities are in higher demand than ever.
Some terpene-heavy strains gaining traction include:
- Soap (Sativa Hybrid) – A piney, floral, and citrus-forward strain that is appearing in more North Shore dispensaries.
- Permanent Marker (Hybrid) – Known for its funky, fruity aroma, this strain is expected to be a favorite among Boston’s boutique cannabis market.
- Puro Loco (Sativa) – A zesty cross between Durban Poison and Tangie, offering a vibrant and energetic high.
Local Breeders are Creating Exclusive Crossbreeds
Massachusetts cultivators are experimenting with genetics to produce new high-THC, terpene-rich hybrids. Some up-and-coming crosses include:
- Boston Cream Pie (Hybrid) – A Wedding Cake x Gelato 41 cross, offering a smooth, creamy flavor profile.
- Durban Skunk (Sativa Hybrid) – A fusion of Durban Poison and Skunk #1, bringing together high energy and skunky funk.
- Triple Burger (Indica Hybrid) – A GMO x Animal Mints hybrid, delivering a heavy, sedative effect.
The Rise of CBD-Dominant Strains
With more cannabis consumers looking for functional, balanced effects, there has been a resurgence of CBD-rich strains in Massachusetts. These strains offer relaxation and stress relief without an overwhelming psychoactive experience.
- Harle-Tsu (Hybrid) – A 15:1 CBD:THC ratio, perfect for calm focus and relaxation.
- Cherry Wine (Indica Hybrid) – A smooth CBD strain with earthy cherry notes, great for easing anxiety.
- ACDC 2.0 (Sativa Hybrid) – A CBD strain that provides alertness without the high, ideal for daytime use.
Limited-Edition “Drop Strains” are Reshaping the Market
Massachusetts dispensaries are embracing boutique, small-batch strain drops, releasing exclusive genetics in limited quantities. This trend is attracting strain hunters and connoisseurs looking for rare, high-end cannabis.
Some anticipated releases in 2025 include:
- Biscotti Pancakes (Hybrid) – A cross of Biscotti x London Pound Cake, with sweet, buttery flavors.
- Purple Z (Sativa Hybrid) – A Zkittlez-based strain, appearing in select New England grower collaborations.
- Lemon Royale (Sativa) – A tangy, uplifting strain expected to hit Massachusetts shelves in the second half of 2025.
Find Your Perfect Strain in 2025
Massachusetts consumers have more strain variety than ever, with a mix of classic favorites and exciting new releases shaping the cannabis landscape. Whether you're looking for a potent indica for deep relaxation, a flavorful hybrid for a balanced experience, or a high-energy sativa for daytime motivation, there’s something for everyone.
And remember—On Root’s delivery service is coming soon, making it even easier to get your favorite strains delivered straight to your door.